Mapping DROSHA’s cleavage sites

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Each cell of our body is the result of an orchestra of sophisticated mechanisms that control which genes are and are not expressed at any given time. Partly, this is possible thanks to the coordination of several types of RNA molecules, like microRNAs (miRNAs). Researchers have developed a new technique called fCLIP-seq that analyzes the miRNA fragments created by the RNA-cleaving protein DROSHA. It is expected that this study will open up new pathways to understand the role of DROSHA in such important biological phenomena.

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New tools visualize where bacterial species live in the gut, control their activity

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It is now possible to simultaneously visualize multiple bacterial strains in the gut by making them express unique combinations of fluorescent proteins. This approach allowed the researchers to pinpoint the location of the bacteria in the gut based on the rainbow of colors they emitted. Additionally, these tools also allowed precise control of the activity of bacterial genes in real time and in specific locations.

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Towards a liveable future

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Humans have influenced nature since as early as the Ice Age, and over the past century our impact has become even greater with our many new technologies and a growing world population. Researchers have studied this impact and how we can keep it within reasonable limits so that nature can be preserved. We cannot do without nature: we need it for our food and for raw materials, as well as for relaxation.

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